Colts vs Jaguars Picks, Predictions, and Best Bets for Week 5: Thomas Takes Flight Against Indy

The winless Jacksonville Jaguars host the Indianapolis Colts in an AFC South showdown at EverBank Stadium on Sunday.

Jacksonville rookie Brian Thomas headlines our Colts vs. Jaguars predictions, with Jags quarterback Trevor Lawrence and the air attack set up for success against a weak Indy pass defense in Week 5.

Find out more in our NFL picks for October 6.

Colts vs Jaguars prediction

My best betBrian Thomas Over 50.5 receiving yards (-135 at BetMGM)

My analysis

Jacksonville Jaguars rookie Brian Thomas has been a lone bright spot through the first four weeks, boasting 17 receptions for 275 yards and a pair of scores on just 26 targets. His 12.8 aDOT and 10.6 yards per target are high-end marks, and he’s c…